GENETIC PATTERN, ORTHODONTIC AND SURGICAL MANAGEMENT OF MULTIPLE SUPPLEMENTARY IMPACTED TEETH IN A RARE, CLEIDOCRANIAL DYSPLASIA PATIENT: A CASE REPORT

Background: Cleidocranial dysplasia (CCD) is a rare, autosomal dominant skeletal dysplasia with a prevalence of one per ANTI-STRESS million births.The main causes of CCD are mutations in the core-binding factor alpha-1 (CBFA1) or runt-related transcription factor-2 (RUNX2), located at the 6p21 chromosomal region.RUNX2 plays important roles in osteo

Biofilms are microbial communities characterized by their adhesion to solid surfaces and the production of a matrix of exopolymeric substances (EPS), consisting of polysaccharides, proteins, DNA and lipids, which surround the microorganisms lending structural integrity and a unique biochemical profile to the biofilm.Biofilm formation enhances the a

In COPD patients, non-anemic iron deficiency (NAID) is a common systemic manifestation.We hypothesized that in COPD patients with NAID, iron therapy may improve systemic oxidative stress.The FACE (Ferinject assessment in patients Maintenance Kit with COPD and iron deficiency to improve exercise tolerance) study was a single-blind, unicentric, paral